Most recent Publications

Pierrat, O.A., Mikitova, V., Bush, M.S., Browning, K.S., Doonan, J.H. (2007)  Control of protein translation by phosphorylation of the mRNA 5'-cap-binding complex. Biochem Soc Trans. 35: 1634-47.

Treder, K., Kneller, E.L., Allen, E.M., Wang, Z., Browning, K.S, and Miller, W.A. (2007)  The 3’ Cap-Independent Translation Element of Barley Yellow Dwarf Virus Binds eIF4F via the eIF4G Subunit to Initiate Translation.  RNA 14: 134-47.

Monzingo, A.F., Dhaliwal, S., Dutt-Chaudhuri, A., Lyon, A., Sadow, J., Hoffman, D.W.,  Robertus, J.D., and Browning, K.S. (2007) The Structure of Translation Initiation Factor eIF4E from Wheat Reveals a Novel Disulfide Bond.  Plant Phys. 143: 1504-1518.

Mayberry, L.K., Dennis, M.D., Allen, M.L., Nitka, K.A., Murphy, P.A., Campbell, L.  and Browning, K.S. (2007) Expression and purification of recombinant wheat translation initiation factors eIF1, eIF1A, eIF4A, eIF4B, eIF4F, eIF(iso)4F and eIF5.  Meth. Enzymol. 430:397-408.

Nicaise, V., Gallois, J.L., Chafiai, F., Allen, M.l., Schurdi-Levraud, V., Browning, K.S., Candresse, T., Caranta, C., Le Gall, O., German-Retana, S. (2007) Coordinated and selective recruitment of eIF4E and eIF4G factors for potyvirus infection in Arabidopsis thaliana FEBS Lett.  581:  1041-1046.

Mayberry, L. and Browning, K.S. (2006) In vitro translation of plant viral RNA. Current Protocols in Microbiology,  pp. 16K1.1-16K1.12. Wiley, New York.

Browning, K.S. (2004) Plant translation initiation factors: it is not easy to be green. Biochem. Soc. Trans. (2004) 32: 589–591.

Pavel, I., Belcher, A. and Browning, K.S. (2004) A Method for Coupled Transcription and Aminoacylation of cys-tRNA. Anal. Biochem: 335: 192-195.

Park, H.S., Browning, K.S., Hohn, T., and Ryabova, L.A. (2004) Eucaryotic initiation factor 4B controls eIF3-mediated ribosomal entry of viral reinitiation factor. EMBO J. 23: 1381-91

Gazo, B.G., Murphy, P., Gatchel, J.R. and Browning, K.S. (2004) A novel interaction of cap-binding protein complexes eIF4F and eIF(iso)4F with a region in the 3' untranslated region of Satellite Tobacco Necrosis Virus. J. Biol. Chem. 279: 13584 - 13592.

Dhaubhadel S, Browning KS, Gallie DR, Krish P. (2002) Brassinosteroid functions to protect the translational machinery and heat-shock protein synthesis following thermal stress. Plant J. 29: 681-91.

Zeenko VV, Ryabova LA, Spirin AS, Rothnie HM, Hess D, Browning KS, Hohn T. (2002) Eukaryotic elongation factor 1A interacts with the upstream pseudoknot domain in the 3' untranslated region of tobacco mosaic virus RNA. J Virol. 76:5678-91.

Duprat, A., Caranta, C., Revers, F., Menand, B., Browning, K.S., Robaglia, C. (2002) The Arabidopsis eukaryotic initiation factor (iso)4E is dispensable for plant growth but required for susceptibility to potyviruses. Plant Journal 32: 927-34.

Daniel R. Gallie and Karen S. Browning (2001) eIF4G functionally differs from eIFiso4G in promoting internal initiation, cap-independent translation, and translation of structured mRNAs. J Biol Chem. 276: 36951-36960.

Hyun-Sook Park, Axel Himmelbach, Karen S. Browning, Thomas Hohn, and Lyubov A. Ryabova (2001) A Plant Viral ''Reinitiation'' Factor Interacts with the Host Translational Machinery. Cell 106: 723-733.

Miller WA, Waterhouse PM, Brown JW, Browning KS (2001) The RNA world in plants: post-transcriptional control III. Plant Cell. 13:1710-1717.

Karen S. Browning, Daniel R. Gallie, John W. B. Hershey, Alan G. Hinnebusch, Umadas Maitra, William C. Merrick and Chris Norbury (2001) Unified nomenclature for the subunits of eukaryotic initiation factor 3 TIBS 26, 284.

Elizabeth A. Burks, Paula P. Bezerra, Hahn Le, Daniel R. Gallie, and Karen S. Browning (2001) Plant initiation factor 3 subunit composition resembles mammalian initiation factor 3 and has a novel subunit. J. Biol. Chem. 276, 2122-2131.

Hanh Le, Karen S. Browning, and Daniel R. Gallie (2000) The Phosphorylation State of Poly(A)-binding Protein Specifies Its Binding to Poly(A) RNA and Its Interaction with Eukaryotic Initiation Factor (eIF) 4F, eIFiso4F, and eIF4B. J. Biol. Chem., 275, 17452-17462.

Miguel Angel Freire, Colette Tourneur, Fabienne Granier, Jacques Camonis, Abdelhak El Amrani, Karen S. Browning, Christophe Robaglia (2000). Plant lipoxygenase 2 is a translation initiation factor-4E-binding protein. Plant Molecular Biology 44: 129-140 

 Previous Representative Publications

Anneke M. Metz, Karen C. H. Wong, Susanna A. Malmström, Karen S. Browning (1999). Eukaryotic Initiation Factor 4B from Wheat and Arabidopsis thaliana Is a Member of a Multigene Family. BBRC 266: 314-321

Theo W. Dreher, Olke C. Uhlenbeck, and Karen S. Browning (1999) . Quantitative Assessment of EF-1a·GTP Binding to Aminoacyl-tRNAs, Aminoacyl-viral RNA, and tRNA Shows Close Correspondence to the RNA Binding Properties of EF-Tu.  J. Biol. Chem. 274: 666-672

Chang, L., Young, W.Y., Browning, K.S. and Roth, D. (1999) Specific in vitro phosphorylation of plant eIF2a by eukaryotic eIF2a kinases. Plant Mol. Biol. 41: 363-370.

Hanh Le, Karen S. Browning, and Daniel R. Gallie (1998). The Phosphorylation State of the Wheat Translation Initiation Factors eIF4B, eIF4A, and eIF2 Is Differentially Regulated during Seed Development and Germination. J. Biol. Chem. 273: 20084-20089.

Kelley A. Ruud, Christopher Kuhlow, Dixie J. Goss, and Karen S. Browning (1998).Identification and Characterization of a Novel Cap-binding Protein

Gallie, D. R., Le, H., Caldwell, C. and Browning, K. S. (1998) Analysis of translation elongation factors from wheat during development and following heat shock. Biochem. Biophys. Res. Commun. 245: 295-300.

Shanping Wang, Karen S. Browning and W.Allen Miller (1997). A viral sequence in the 3-untranslated region mimics a 5 cap in facilitating translation of uncapped mRNA. EMBO J. 16: 4107-4116 

Anneke M. Metz, Karen S. Browning (1997). Assignment of the b-Subunit of Wheat eIF2 by Protein and DNA Sequence Analysis and Immunoanalysis. Archives of Biochem. Biophys. 342: 187-189.

Hanh Le, Robert L. Tanguay, M. Luisa Balasta, Chin-Chuan Wei, Karen S. Browning, Anneke M. Metz, Dixie J. Goss, and Daniel R. Gallie (1997).Translation Initiation Factors eIF-iso4G and eIF-4B Interact with the Poly(A)-binding Protein and Increase Its RNA Binding Activity.  J. Biol. Chem. 272: 16247-16255.

Daniel R. Gallie, Hanh Le, Christian Caldwell, Robert L. Tanguay, Nam X. Hoang, and Karen S. Browning (1997) The Phosphorylation State of Translation Initiation Factors Is Regulated Developmentally and following Heat Shock in Wheat.  J. Biol. Chem. 272: 1046-1053.

Anneke M. Metz and Karen S. Browning (1996). Mutational Analysis of the Functional Domains of the Large Subunit of the Isozyme Form of Wheat Initiation Factor eIF4F.  J. Biol. Chem. 271: 31033-31036.

Browning, K.S. (1996) The Plant Translational Apparatus. Pl. Mol. Biol. Plant Mol Biol 32:107-44.

 
 
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