Philip D. Magnus Research Group

Magnus, Philip; Ghavimi, Bahman; Coe, Jotham; Access to 7β-analogs of codeine with mixed μ/δ agonist activity via 6,7-α-epoxide opening. Bioorganic & Medicinal Chemistry Letters (2013) 23, 4870- 4874

Magnus, Philip; Brozell, Alec; Lewis Acid Catalyzed α-Functionalization of Ketals for the Regioselective Synthesis of α-Carbamoyl Ketals. Organic Letters (2012) 14 (15), 3952-3954

Magnus, Philip; Freund, Wesley A.; Moorhead, Eric J.; Formal Synthesis of (±)-Methyl Rocaglate Using an Unprecedented Acetyl Bromide Mediated Nazarov Reaction. Journal of the American Chemical Society (2012) 134 (14), 6140-6142

Magnus, Philip; Rivera, Heriberto; Lynch, Vince. Concise Formal Total Synthesis of Platensimycin Mediated by a Stereoselective Autoxidation and Hydroxyl Group Directed Conjugative Reduction. Organic Letters (2010) 12 (24), 5677-5679 (pdf click here)

Magnus, Philip; Garizi, Negar; Seibert, Kimberly A.; Ornholt, Alexandra. Synthesis of Carbamates from Diethoxycarbonyl Hydrazine Derivatives by E1cB Eliminative Cleavage of the N-N' Bond Rather than Reduction. Organic Letters (2009)
11 (24), 5646-5648 (pdf click here)

Magnus, Philip; Sane, Neeraj; Fauber, Benjamin P.; Lynch, Vince. Concise Syntheses of (-)-Galanthamine and (+/-)-Codeine via Intramolecular Alkylation of a Phenol Derivative. Journal of the American Chemical Society (2009) 131(44), 16045-16047 (pdf click here)

Magnus, Philip; Littich, Ryan. Intramolecular Cyclopropene-Furan [2 + 4] Cycloaddition followed by a Cyclopropylcarbinyl Rearrangement to Synthesize the BCD Rings of Cortistatin A. Organic Letters (2009), 11 (17), 3938–3941 (pdf click here)

Black, Phillip J.; Hecker, Evan A.; Magnus, Philip. Studies towards the synthesis of the marine alkaloid chartelline C. Tetrahedron Letters (2007), 48(36), 6364-6367.

Cheung, Chi-Ming; Goldberg, Frederick W.; Magnus, Philip; Russell, Claire J.; Turnbull, Rachel; Lynch, Vince. An Expedient Formal Total Synthesis of (-)-Diazonamide A via a Powerful, Stereoselective O-Aryl to C-Aryl Migration To Form the C10 Quaternary Center. Journal of the American Chemical Society (2007), 129(40), 12320-12327.

Magnus, Philip; Padilla, Angela I. Proposed biogenetic origin of secu'amamine a from allosecurinine: A model study to support the intermediacy of the putative aziridinium ion. [Erratum to document cited in CA145:293204]. Organic Letters (2006), 8(22), 5177.

Magnus, Philip; Turnbull, Rachel. Methodology for the synthesis of the core EFGH rings of diazonamide A. Tetrahedron Letters (2006), 47(36), 6461-6464.

Magnus, Philip; Padilla, Angela I. Proposed Biogenetic Origin of Secu'amamine A from Allosecurinine: A Model Study To Support the Intermediacy of the Putative Aziridinium Ion. Organic Letters (2006), 8(16), 3569-3571.

Magnus, Philip; Turnbull, Rachel. Thermal and acid-catalyzed Hofmann-Martius rearrangement of 3-N-aryl-2-oxindoles into 3-(arylamino)-2-oxindoles. Organic Letters (2006), 8(16), 3497-3499.

Goldberg, Frederick W.; Magnus, Philip; Turnbull, Rachel. A Mild Thermal and Acid-Catalyzed Rearrangement of O-Aryl Ethers into ortho-Hydroxy Arenes. Organic Letters (2005), 7(20), 4531-4534.

Magnus, Philip; Stent, Matthew A. H. Stereospecific Synthesis of ( )-1,2-Anhydro Methyl Rocaglate. Organic Letters (2005), 7(18), 3853-3855.

Magnus, Philip; Matthews, Kenneth S. Synthesis of the Tetrahydroisoquinoline Alkaloid ( )-Renieramycin G and a ( )-Lemonomycinone Analogue from a Common Intermediate. Journal of the American Chemical Society (2005), 127(36), 12476-12477.

Magnus, Philip; Venable, Jennifer D.; Shen, Lan; Lynch, Vince. Some reactions of persistent benzofuranone radicals related to the 'old' diazonamide structure. Tetrahedron Letters (2005), 46(4), 707-710.

Magnus, Philip; Matthews, Kenneth S.; Lynch, Vince. New Strategy for the Synthesis of Tetrahydroisoquinoline Alkaloids. Organic Letters (2003), 5(12), 2181-2184.

Magnus, Philip; Rainey, Trevor; Lynch, Vince. Synthesis of functionalized bicyclo[3.2.1]octan-6-ones for diterpenoids: allylsilane directed Pummerer reaction: insertion reactions of diazoketones. Tetrahedron Letters (2003), 44(12), 2459-2461.

Magnus, Philip; Fielding, Mark R.; Wells, Charles; Lynch, Vince. Stereoselective synthesis of the tricyclic core ABC-rings of nakadomarin and manzamine from a common intermediate. Tetrahedron Letters (2002), 43(6), 947-950.

Magnus, Philip; Ollivier, Cyril. Synthesis of the hydroazulene portion of guanacastepene A using a [2.3]sigmatropic sulfoxide rearrangement: observations on silyl enol ether electrophilic chemistry for the introduction of the C-13 hydroxyl group. Tetrahedron Letters (2002), 43(52), 9605-9609.

Kreisberg, Jennifer D.; Magnus, Philip; Shinde, Shirin. Pummerer reaction methodology for the synthesis of 5-thiophenyl substituted oxazoles. Tetrahedron Letters (2002), 43(41), 7393-7396.

Magnus, Philip; Gazzard, Lewis; Hobson, Lindsay; Payne, Andrew H.; Rainey, Trevor J.; Westlund, Neil; Lynch, Vince. Synthesis of the Kopsia alkaloids ( )-pauciflorine B, ( )-lahadinine B, ( )-kopsidasine, ( )-kopsidasine-N-oxide, ( )-kopsijasminilam and ( )-11-methoxykopsilongine. Tetrahedron (2002), 58(17), 3423-3443.

Hobson, Lindsay A.; Magnus, Philip. Peroxides in ethyl acetate. Chemical & Engineering News (2000), 78(51), 2.

Carter, Rich; Hodgetts, Kevin; McKenna, Jeff; Magnus, Philip; Wren, Stephen. Studies on the stereoselective synthesis of the marine antitumor agent eleutherobin. Tetrahedron (2000), 56(26), 4367-4382.